tel: 0207 132 1440  email:

Dr Yiannis Kallis  BA MA PhD MRCP


I am a Consultant Hepatologist and Gastroenterologist at the Royal London Hospital (Barts Health NHS Trust), and Honorary Consultant Transplant Hepatologist at the Royal Free London NHS Foundation Trust.


Training and experience

I studied medicine at Trinity College Cambridge. My basic and higher medical training in internal medicine and gastroenterology was undertaken across several London teaching hospitals, with subspecialty training in hepatology and pancreato-biliary medicine completed in the renowned centres at the Royal Free Hospital, Imperial College Healthcare and University College London Hospital. My research into liver fibrosis and regeneration, funded by a Medical Research Council Fellowship, led to the award of a PhD from Imperial College London. I have worked as an NHS consultant for five years.


Skills and expertise

I have expertise in the diagnosis and treatment of a full range of gastrointestinal and liver diseases with a particular focus on the management of liver test abnormalities, chronic diseases such as fatty liver, viral hepatitis, alcohol-related liver disorders, and on disorders of the pancreas, gallbladder and bile ducts. I have extensive experience in the management of complications of cirrhosis and liver transplantation, and offer non-invasive testing of liver scarring.


I am a highly skilled advanced endoscopist and provide a full range of diagnostic and therapeutic upper intestinal endoscopy and colonoscopy, with an emphasis on patient safety and comfort. I have particular expertise in therapeutic endoscopy of the bile duct and pancreas (ERCP) and am often referred complex cases.



I remain active in clinical research and hold an Honorary Clinical Senior Lecturer position at Barts and the London School of Medicine and Dentistry. I am a principal investigator for multi-centre clinical trials on new treatments for liver disease and maintain a particular research interest in novel endoscopic therapies for pancreatic and bile duct malignancies.


Memberships and other roles

I am a member of the Royal College of Physicians, the British Society of Gastroenterology, and the British Association for the Study of the Liver.



Kallis YN, Phillips N, Steel A, Kaltsidis C, Vlavianos P, Habib N, Westaby D. Analysis of Long-Term Outcome after Endoscopic Radiofrequency Ablation of Biliary Strictures in Pancreatic Cancer Suggests Potential Survival Benefit. Dig Dis Sci. 2015 Jun 3. [Epub ahead of print]


Gill US, Zissimopoulos A, Al-Shamma S, Burke K, McPhail MJ, Barr DA, Kallis YN, Marley RT, Kooner P, Foster GR, Kennedy PT. Assessment of bone mineral density in tenofovir-treated patients with chronic hepatitis B: can the fracture risk assessment tool identify those at greatest risk? J Infect Dis. 2015;211(3):374-82


Kallis YN, Scotton CJ, Mackinnon AC, Goldin RD, Wright NA, Iredale JP, Chambers RC, Forbes SJ. Proteinase activated receptor 1 mediated fibrosis in a mouse model of liver injury: a role for bone marrow derived macrophages. PLoS One 2014; 9(1): e86241.


Kalaitzakis E, Webster GJ, Oppong KW, Kallis YN, Vlavianos P, Huggett M, Dawwas MF, Lekharaju V, Hatfield A, Westaby D, Sturgess R. Diagnostic and therapeutic utility of single-operator peroral cholangioscopy for indeterminate biliary lesions and bile duct stones. Eur J Gastroenterol Hepatol. 2012; 24(6):656-64


Lin WR, Inatomi O, Lee CY, Kallis YN, Otto WR, Jeffery R, Poulsom R, Alison MR. Bone marrow-derived cells contribute to cerulein-induced pancreatic fibrosis in the mouse. Int J Exp Pathol. 2012;93(2):130-8

Kallis YN, Robson AJ, Fallowfield JA, Thomas HC, Alison MR, Wright NA, Goldin RD, Iredale JP, Forbes SJ. Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response. Gut 2011; 60(4): 525-33.


Kallis YN, Forbes SJ. The bone marrow and liver fibrosis: friend or foe? Gastroenterology 2009; 137(4): 1218-21.


Kallis YN, Alison MR, Forbes SJ. Bone marrow stem cells and liver disease. Gut 2007; 56(5): 716-724.


Russo FP, Kallis YN, Alison MR, Forbes SJ. Bone marrow cells in the liver: diverse cells, diverse effects. Hepatology 2007; 46(2): 604-5.


Kallis YN, SJ Forbes. Stem cells in liver repair. The Biochemist 2006; 28(1):



Tel: 020 7132 1440    email:

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